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Myelofibrosis Awareness

Myelofibrosis


What is Myelofibrosis?
Myelo= Marrow
Fibrosis= Accumulation of scar tissue

Simply put, it is a blood condition in which the bone marrow is replaced by scar tissue.
What happens?

The bone marrow is a soft fatty tissue inside of your bones.  This tissue is replaced by scar tissue.  Due to the accumulation of scar tissue, blood cells do not grow correctly.  Blood cells are very important to the body. Red blood cells carry oxygen to your tissues and organs, white blood cells fight infection, and platelets help blood clot.  Lack of healthy blood cells leads to anemia, bleeding problems, and high risk for infections.  Due to the lack of fully developed blood cells, other organs such as the liver and spleen try to make some of the cells.  This causes these organs to swell.

What is the cause?

Research suggests it may be due to abnormal blood stem cells in the bone marrow. 

What are the risk factors?

Currently there are no known risk factors.

What are the symptoms?

-Fullness, discomfort of pain in the upper left side of the Stomach due to an enlarged spleen

-Bone/Joint Pain

-Bleeding or Bruising Easily

-Feeling tired and/or weak (Fatigue)

-Shortness of breath with exercise
-Increased infections

-Pale mucus membranes (pale gums for example)

What are the treatments?

Each case is different but common treatments include:

-Blood Transfusions
-Medications
-Removal of the Spleen

What if treatments don’t work?

Many people diagnosed with life-threatening blood conditions will eventually need a bone marrow transplant.

What is a bone marrow transplant?

A bone marrow transplant is when a donor’s healthy blood forming cells are put into the bloodstream of a patient such as Syreeta.  These cells then begin to grow and make healthy red blood cells, white blood cells and platelets.  

There are two types of bone marrow transplant procedures. To learn more about the bone marrow transplant procedure visit “Be the Match”.

Want to "Be the Match"?

Come out on August 10, 2014 and join the registry 
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